Case report Genotyping of Toxoplasma gondii strain directly from human CSF samples of congenital toxoplasmosis clinical case
نویسندگان
چکیده
1 Department of Molecular Medicine and Medical Biotechnology, Federico II University Medical School, Naples, Italy; 2 CEINGE-Advanced Biotechnologies, Naples, Italy; 3 Department of Sciences and Technologies, University of Sannio, Benevento, Italy; 4 Department of Neuroscience, Reproductive Sciences and Odontostomatology, School of Medicine, University of Naples Federico II, Naples, Italy; 5 Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy; 6 Department of Neuroradiology, Santobono-Pausilipon Children’s Hospital of Naples, Italy; 7 Neonatal Intensive Care Unit, Santobono-Pausilipon Children’s Hospital of Naples, Italy. § Current address: Laboratory of Molecular Microbiology and Biotechnology, Department of Medical Biotechnologies, University of Siena, Siena, Italy.
منابع مشابه
Genotyping of Toxoplasma gondii strain directly from human CSF samples of congenital toxoplasmosis clinical case.
This report describes a case of congenital toxoplasmosis in a newborn in Southern Italy. A pregnant mother had been admitted at the 20th week of her pregnancy on account of pharyngodynia and laterocervical lymphadenopathy. Although serological testing of the mother's serum documented a seroconversion with positive IgG and IgM anti-Toxoplasma antibodies during II trimester, the woman refused to ...
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Very limited data exists on the genetic diversity of Toxoplasma gondii from Eastern Europe. We present the first Romanian case of symptomatic congenital toxoplasmosis in which the T. gondii strain was isolated after inoculation in mice of a cerebrospinal fluid sample from a living neonate. The T. gondii strain was genotyped with 15 microsatellite markers distributed on 10 of the 14 chromosomes ...
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Introduction: Congenital toxoplasmosis is caused by acute toxoplasma gondii infection of mother during pregnancy, which may lead to such serious complications as stillbirth, ophthalmologic and neurologic disorders. The aim of this study was to determine the incidence of toxoplasmosis in pregnant women and their neonates, and disease complications. Methods: In this prospective cohort study, blo...
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Toxoplasma gondii strains were genotyped directly from blood samples of patients with ocular toxoplasmosis. Analysis of nontranscribed spacer 2 revealed that all detected strains belonged to type I, suggesting an association of ocular toxoplasmosis with this type. The method shows the usefulness of blood samples for genotyping in ocular toxoplasmosis.
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Background: Toxoplasmosis is one of the most important food-borne diseases distributed worldwide. In order to determinate the involvement of poultry meat in clinical toxoplasmosis, this study aimed to genetic characterization of Toxoplasma gondii in tissue samples of serologically positive chickens of Tunisia using Polymerase Chain Reaction (PCR). Methods: Trail of isolation of local T. gondii...
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